Many of the brand name products have been discontinued by their manufacturers however, equivalent, lower-cost generics are available for these brands.

generic and brand name benzodiazepines, their common uses and duration of action. he Centers for Disease Control and Prevention recommends that doctors avoid prescribing Xanax and other benzodiazepines with opioid pain medication whenever possible.įlumazenil is a benzodiazepine antagonist antidote that can be given intravenously in the emergency setting to reverse the effects of a benzodiazepine overdose. Abuse, misuse, addiction, physical dependence, and withdrawal reactions greatly increases with use of this drug class.

When benzodiazepines are combined with other sedatives, opiates or alcohol, the risk of serious side effects such as profound sedation, respiratory depression, coma, and death may occur.

As controlled substances, all benzodiazepines have the potential for abuse, addiction and diversion.Ī Boxed Warning, the FDA's most stringent safety warning, exists on all benzodiazepine product information. There are many options available within the class, and most benzodiazepines are now available generically, making them affordable for most people.Īll benzodiazepines are listed as DEA schedule IV controlled substances.

to induce relaxation and loss of memory of medical procedures or surgeryīenzodiazepines are a large drug class and have a long history of development, starting with the first FDA-approvals in the 1960s, chloridiazepoxide (Librium) and diazepam (Valium).

Common examples of benzodiazepines include alprazolam (brand: Xanax), diazepam (brand: Valium) and lorazepam (brand: Ativan). Because of this, some benzodiazepines work better than others in the treatment of particular conditions. Benzodiazepines work by blocking excessive activity of nerves in the brain and other areas in the central nervous system.Īs a class, benzodiazepines are similar in how they work in the brain but have different potencies and durations of actions. Last updated on Jan 20, 2022.īenzodiazepines are a class of medications that work in the central nervous system and are used for a variety of medical conditions, such as anxiety, seizures, and for alcohol withdrawal. Medically reviewed by Leigh Ann Anderson, PharmD.

Antidote for benzodiazepine overdose